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Crystal Structure of Human Protein N-Terminal Glutamine Amidohydrolase, an Initial Component of the N-End Rule Pathway

The N-end rule states that half-life of protein is determined by their N-terminal amino acid residue. N-terminal glutamine amidohydrolase (Ntaq) converts N-terminal glutamine to glutamate by eliminating the amine group and plays an essential role in the N-end rule pathway for protein degradation. He...

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Detalles Bibliográficos
Autores principales: Park, Mi Seul, Bitto, Eduard, Kim, Kyung Rok, Bingman, Craig A., Miller, Mitchell D., Kim, Hyun-Jung, Han, Byung Woo, Phillips, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214742/
https://www.ncbi.nlm.nih.gov/pubmed/25356641
http://dx.doi.org/10.1371/journal.pone.0111142