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Type II transmembrane domain hydrophobicity dictates the cotranslational dependence for inversion

Membrane insertion by the Sec61 translocon in the endoplasmic reticulum (ER) is highly dependent on hydrophobicity. This places stringent hydrophobicity requirements on transmembrane domains (TMDs) from single-spanning membrane proteins. On examining the single-spanning influenza A membrane proteins...

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Detalles Bibliográficos
Autores principales: Dou, Dan, da Silva, Diogo V., Nordholm, Johan, Wang, Hao, Daniels, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214783/
https://www.ncbi.nlm.nih.gov/pubmed/25165139
http://dx.doi.org/10.1091/mbc.E14-04-0874