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Type II transmembrane domain hydrophobicity dictates the cotranslational dependence for inversion
Membrane insertion by the Sec61 translocon in the endoplasmic reticulum (ER) is highly dependent on hydrophobicity. This places stringent hydrophobicity requirements on transmembrane domains (TMDs) from single-spanning membrane proteins. On examining the single-spanning influenza A membrane proteins...
Autores principales: | Dou, Dan, da Silva, Diogo V., Nordholm, Johan, Wang, Hao, Daniels, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214783/ https://www.ncbi.nlm.nih.gov/pubmed/25165139 http://dx.doi.org/10.1091/mbc.E14-04-0874 |
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