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The N-Terminus of Murine Leukaemia Virus p12 Protein Is Required for Mature Core Stability

The murine leukaemia virus (MLV) gag gene encodes a small protein called p12 that is essential for the early steps of viral replication. The N- and C-terminal regions of p12 are sequentially acting domains, both required for p12 function. Defects in the C-terminal domain can be overcome by introduci...

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Detalles Bibliográficos
Autores principales: Wight, Darren J., Boucherit, Virginie C., Wanaguru, Madushi, Elis, Efrat, Hirst, Elizabeth M. A., Li, Wilson, Ehrlich, Marcelo, Bacharach, Eran, Bishop, Kate N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214797/
https://www.ncbi.nlm.nih.gov/pubmed/25356837
http://dx.doi.org/10.1371/journal.ppat.1004474