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Identification of the Microsporidian Encephalitozoon cuniculi as a New Target of the IFNγ-Inducible IRG Resistance System

The IRG system of IFNγ-inducible GTPases constitutes a powerful resistance mechanism in mice against Toxoplasma gondii and two Chlamydia strains but not against many other bacteria and protozoa. Why only T. gondii and Chlamydia? We hypothesized that unusual features of the entry mechanisms and intra...

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Detalles Bibliográficos
Autores principales: da Fonseca Ferreira-da-Silva, Marialice, Springer-Frauenhoff, Helen Maria, Bohne, Wolfgang, Howard, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214799/
https://www.ncbi.nlm.nih.gov/pubmed/25356593
http://dx.doi.org/10.1371/journal.ppat.1004449