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Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting
A fundamental feature of immune systems is the ability to distinguish pathogenic from self and commensal elements, and to attack the former but tolerate the latter(1). Prokaryotic CRISPR-Cas immune systems defend against phage infection using Cas nucleases and small RNA guides that specify one or mo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214910/ https://www.ncbi.nlm.nih.gov/pubmed/25174707 http://dx.doi.org/10.1038/nature13637 |