‘N-of-1-pathways’ unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine

BACKGROUND: The emergence of precision medicine allowed the incorporation of individual molecular data into patient care. Indeed, DNA sequencing predicts somatic mutations in individual patients. However, these genetic features overlook dynamic epigenetic and phenotypic response to therapy. Meanwhil...

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Detalles Bibliográficos
Autores principales: Gardeux, Vincent, Achour, Ikbel, Li, Jianrong, Maienschein-Cline, Mark, Li, Haiquan, Pesce, Lorenzo, Parinandi, Gurunadh, Bahroos, Neil, Winn, Robert, Foster, Ian, Garcia, Joe G N, Lussier, Yves A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Research and Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215042/
https://www.ncbi.nlm.nih.gov/pubmed/25301808
http://dx.doi.org/10.1136/amiajnl-2013-002519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215042/
https://www.ncbi.nlm.nih.gov/pubmed/25301808
http://dx.doi.org/10.1136/amiajnl-2013-002519

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