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Irreversible hyperoxidation of peroxiredoxin 2 is caused by tert-butyl hydroperoxide in human red blood cells

Peroxiredoxin 2 (Prx2) is the third most abundant protein in red blood cells (RBCs). In this study, we have succeeded in implementing the rapid and simultaneous detection of the hyperoxidized (Prx2-SO(2/3)) and reduced (Prx2-SH) forms of Prx2 in human RBCs using reverse phase high-performance liquid...

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Detalles Bibliográficos
Autores principales: Ishida, Y.I., Takikawa, M., Suzuki, T., Nagahama, M., Ogasawara, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215121/
https://www.ncbi.nlm.nih.gov/pubmed/25379381
http://dx.doi.org/10.1016/j.fob.2014.10.003