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Chromosome rearrangements via template switching between diverged repeated sequences

Recent high-resolution genome analyses of cancer and other diseases have revealed the occurrence of microhomology-mediated chromosome rearrangements and copy number changes. Although some of these rearrangements appear to involve nonhomologous end-joining, many must have involved mechanisms requirin...

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Detalles Bibliográficos
Autores principales: Anand, Ranjith P., Tsaponina, Olga, Greenwell, Patricia W., Lee, Cheng-Sheng, Du, Wei, Petes, Thomas D., Haber, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215184/
https://www.ncbi.nlm.nih.gov/pubmed/25367035
http://dx.doi.org/10.1101/gad.250258.114