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Coordination of insulin and Notch pathway activities by microRNA miR-305 mediates adaptive homeostasis in the intestinal stem cells of the Drosophila gut

Homeostasis of the intestine is maintained by dynamic regulation of a pool of intestinal stem cells. The balance between stem cell self-renewal and differentiation is regulated by the Notch and insulin signaling pathways. Dependence on the insulin pathway places the stem cell pool under nutritional...

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Detalles Bibliográficos
Autores principales: Foronda, David, Weng, Ruifen, Verma, Pushpa, Chen, Ya-Wen, Cohen, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215186/
https://www.ncbi.nlm.nih.gov/pubmed/25367037
http://dx.doi.org/10.1101/gad.241588.114