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Target RNA capture and cleavage by the Cmr type III-B CRISPR–Cas effector complex

The effector complex of the Cmr/type III-B CRISPR (clustered regularly interspaced short palindromic repeat)–Cas (CRISPR-associated) system cleaves RNAs recognized by the CRISPR RNA (crRNA) of the complex and includes six protein subunits of unknown functions. Using reconstituted Pyrococcus furiosus...

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Detalles Bibliográficos
Autores principales: Hale, Caryn R., Cocozaki, Alexis, Li, Hong, Terns, Rebecca M., Terns, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215187/
https://www.ncbi.nlm.nih.gov/pubmed/25367038
http://dx.doi.org/10.1101/gad.250712.114