The Chlamydia Effector TarP Mimics the Mammalian Leucine-Aspartic Acid Motif of Paxillin to Subvert the Focal Adhesion Kinase during Invasion

Host cell signal transduction pathways are often targets of bacterial pathogens, especially during the process of invasion when robust actin remodeling is required. We demonstrate that the host cell focal adhesion kinase (FAK) was necessary for the invasion by the obligate intracellular pathogen Chl...

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Detalles Bibliográficos
Autores principales: Thwaites, Tristan, Nogueira, Ana T., Campeotto, Ivan, Silva, Ana P., Grieshaber, Scott S., Carabeo, Rey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215226/
https://www.ncbi.nlm.nih.gov/pubmed/25193659
http://dx.doi.org/10.1074/jbc.M114.604876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215226/
https://www.ncbi.nlm.nih.gov/pubmed/25193659
http://dx.doi.org/10.1074/jbc.M114.604876

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