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The Chlamydia Effector TarP Mimics the Mammalian Leucine-Aspartic Acid Motif of Paxillin to Subvert the Focal Adhesion Kinase during Invasion
Host cell signal transduction pathways are often targets of bacterial pathogens, especially during the process of invasion when robust actin remodeling is required. We demonstrate that the host cell focal adhesion kinase (FAK) was necessary for the invasion by the obligate intracellular pathogen Chl...
Autores principales: | Thwaites, Tristan, Nogueira, Ana T., Campeotto, Ivan, Silva, Ana P., Grieshaber, Scott S., Carabeo, Rey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215226/ https://www.ncbi.nlm.nih.gov/pubmed/25193659 http://dx.doi.org/10.1074/jbc.M114.604876 |
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