Two novel DNA motifs are essential for BACE1 gene transcription

BACE1 gene encodes for β-Site amyloid β precursor protein (APP)-cleaving enzyme1, which is required for generating amyloid β protein(Aβ). Deposition of Aβ in brain plays an essential role in Alzheimer's Disease (AD) pathogenesis. BACE1 gene has a tissue-specific expression pattern and its expre...

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Detalles Bibliográficos
Autores principales: Xiang, Yan, Meng, Shasha, Wang, Jinfeng, Li, Songyang, Liu, Jingru, Li, Hongmei, Li, Tingyu, Song, Weihong, Zhou, Weihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215305/
https://www.ncbi.nlm.nih.gov/pubmed/25359283
http://dx.doi.org/10.1038/srep06864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215305/
https://www.ncbi.nlm.nih.gov/pubmed/25359283
http://dx.doi.org/10.1038/srep06864

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