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Covalent modification of cytoskeletal proteins in neuronal cells by tryptamine-4,5-dione
Serotonin, 5-hydroxytryptamine, is a systemic bioactive amine that acts in the gut and brain. As a substrate of myeloperoxidase in vitro, serotonin is oxidized to tryptamine-4,5-dione (TD), which is highly reactive with thiols. In this work, we successively prepared a monoclonal antibody to quinone-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215393/ https://www.ncbi.nlm.nih.gov/pubmed/25460734 http://dx.doi.org/10.1016/j.redox.2014.08.004 |