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Investigation of -308G>A and -1031T>C Polymorphisms in the TNFA Promoter Region in Polish Peptic Ulcer Patients

BACKGROUND/AIMS: Tumor necrosis factor α (TNF-α) encoded by TNFA is a key mediator in inflammation, a precursor condition for peptic ulceration. Promoter polymorphisms of TNFA that influence its transcriptional activity and TNF-α production are known. TNFA-308G>A (rs1800629) and TNFA-1031T>C (...

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Detalles Bibliográficos
Autores principales: Sałagacka, Aleksandra, Żebrowska, Marta, Jeleń, Agnieszka, Mirowski, Marek, Balcerczak, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215449/
https://www.ncbi.nlm.nih.gov/pubmed/25368751
http://dx.doi.org/10.5009/gnl13224