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High Expression of Ribonucleotide Reductase Subunit M2 Correlates with Poor Prognosis of Hepatocellular Carcinoma

BACKGROUND/AIMS: Ribonucleotide reductase subunit M2 (RRM2) catalyzes the production of deoxynucleotide triphosphates, which are necessary for DNA synthesis. RRM2 has been reported to play an active role in tumor progression, and elevated RRM2 levels have been correlated with poor prognosis for colo...

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Detalles Bibliográficos
Autores principales: Lee, Boin, Ha, Sang Yun, Song, Dae Hyun, Lee, Hyun Woo, Cho, Soo Youn, Park, Cheol-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215454/
https://www.ncbi.nlm.nih.gov/pubmed/25368754
http://dx.doi.org/10.5009/gnl13392