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Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity

Alcoholic liver disease encompasses a wide spectrum of pathogenesis including steatosis, fibrosis, cirrhosis, and alcoholic steatohepatitis. Autophagy is a lysosomal degradation process that degrades cellular proteins and damaged/excess organelles, and serves as a protective mechanism in response to...

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Detalles Bibliográficos
Autores principales: Manley, Sharon, Ni, Hong-Min, Williams, Jessica A., Kong, Bo, DiTacchio, Luciano, Guo, Grace, Ding, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215528/
https://www.ncbi.nlm.nih.gov/pubmed/25460735
http://dx.doi.org/10.1016/j.redox.2014.08.007