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Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity
Alcoholic liver disease encompasses a wide spectrum of pathogenesis including steatosis, fibrosis, cirrhosis, and alcoholic steatohepatitis. Autophagy is a lysosomal degradation process that degrades cellular proteins and damaged/excess organelles, and serves as a protective mechanism in response to...
Autores principales: | Manley, Sharon, Ni, Hong-Min, Williams, Jessica A., Kong, Bo, DiTacchio, Luciano, Guo, Grace, Ding, Wen-Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215528/ https://www.ncbi.nlm.nih.gov/pubmed/25460735 http://dx.doi.org/10.1016/j.redox.2014.08.007 |
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