The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib(®))

Leiomyosarcomas remain challenging tumors to manage and novel therapy strategies besides radiation and conventional chemotherapy are needed. Targeting angiogenesis by inhibition of vascular endothelial growth factor (VEGF) receptor tyrosine kinases (RTKs) of the tumor vasculature with small molecule...

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Detalles Bibliográficos
Autores principales: GAUMANN, ANDREAS K.A., DREXLER, HANNES C.A., LANG, SVEN A., STOELTZING, OLIVER, DIERMEIER-DAUCHER, SIMONE, BUCHDUNGER, ELISABETH, WOOD, JEANETTE, BOLD, GUIDO, BREIER, GEORG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215578/
https://www.ncbi.nlm.nih.gov/pubmed/25340839
http://dx.doi.org/10.3892/ijo.2014.2683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215578/
https://www.ncbi.nlm.nih.gov/pubmed/25340839
http://dx.doi.org/10.3892/ijo.2014.2683

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