Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway

Multiple myeloma (MM) is a clonal plasma cell disorder affecting the immune system with various systemic symptoms. MM remains incurable even with high dose chemotherapy using conventional drugs, thus necessitating development of novel therapeutic strategies. Gossypol (Gos) is a natural polyphenolic...

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Detalles Bibliográficos
Autores principales: SADAHIRA, KEN, SAGAWA, MORIHIKO, NAKAZATO, TOMONORI, UCHIDA, HIDEO, IKEDA, YASUO, OKAMOTO, SHINICHIRO, NAKAJIMA, HIDEAKI, KIZAKI, MASAHIRO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215583/
https://www.ncbi.nlm.nih.gov/pubmed/25231749
http://dx.doi.org/10.3892/ijo.2014.2652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215583/
https://www.ncbi.nlm.nih.gov/pubmed/25231749
http://dx.doi.org/10.3892/ijo.2014.2652

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