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CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration

BACKGROUND: Asthma is characterized by variable airflow obstruction, airway inflammation, airway hyper-responsiveness and airway remodelling. Airway smooth muscle (ASM) hyperplasia is a feature of airway remodelling and contributes to bronchial wall thickening. We sought to investigate the expressio...

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Detalles Bibliográficos
Autores principales: Singh, S R, Sutcliffe, A, Kaur, D, Gupta, S, Desai, D, Saunders, R, Brightling, C E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215601/
https://www.ncbi.nlm.nih.gov/pubmed/24931417
http://dx.doi.org/10.1111/all.12444