DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides

DNA polymerases have evolved for billions of years to accept natural nucleoside triphosphate substrates with high fidelity and to exclude closely related structures, such as the analogous ribonucleoside triphosphates. However, polymerases that can accept unnatural nucleoside triphosphates are desire...

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Detalles Bibliográficos
Autores principales: Laos, Roberto, Thomson, J. Michael, Benner, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215692/
https://www.ncbi.nlm.nih.gov/pubmed/25400626
http://dx.doi.org/10.3389/fmicb.2014.00565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215692/
https://www.ncbi.nlm.nih.gov/pubmed/25400626
http://dx.doi.org/10.3389/fmicb.2014.00565

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