Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction

In vascular smooth muscle cells (VSMC) increased integrin adhesion to extracellular matrix (ECM) proteins, as well as the production of reactive oxygen species (ROS) are strongly stimulated by lysophosphatidic acid (LPA). We hypothesized that LPA-induced generation of ROS increases integrin adhesion...

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Detalles Bibliográficos
Autores principales: Staiculescu, Marius C., Ramirez-Perez, Francisco I., Castorena-Gonzalez, Jorge A., Hong, Zhongkui, Sun, Zhe, Meininger, Gerald A., Martinez-Lemus, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215695/
https://www.ncbi.nlm.nih.gov/pubmed/25400583
http://dx.doi.org/10.3389/fphys.2014.00413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215695/
https://www.ncbi.nlm.nih.gov/pubmed/25400583
http://dx.doi.org/10.3389/fphys.2014.00413

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