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Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction
In vascular smooth muscle cells (VSMC) increased integrin adhesion to extracellular matrix (ECM) proteins, as well as the production of reactive oxygen species (ROS) are strongly stimulated by lysophosphatidic acid (LPA). We hypothesized that LPA-induced generation of ROS increases integrin adhesion...
Autores principales: | Staiculescu, Marius C., Ramirez-Perez, Francisco I., Castorena-Gonzalez, Jorge A., Hong, Zhongkui, Sun, Zhe, Meininger, Gerald A., Martinez-Lemus, Luis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215695/ https://www.ncbi.nlm.nih.gov/pubmed/25400583 http://dx.doi.org/10.3389/fphys.2014.00413 |
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