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G protein-coupled receptors: computer-aided ligand discovery and computational structural analyses in the 2010s

G protein-coupled receptors, or GPCRs, are a large superfamily of proteins found on the plasma membrane of cells. They are involved in most physiological and pathophysiological functions and constitute the target of the majority of marketed drugs. Although these receptors have been historically elus...

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Detalles Bibliográficos
Autor principal: Costanzi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215811/
https://www.ncbi.nlm.nih.gov/pubmed/25505664
http://dx.doi.org/10.1186/2193-9616-1-20