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G protein-coupled receptors: computer-aided ligand discovery and computational structural analyses in the 2010s
G protein-coupled receptors, or GPCRs, are a large superfamily of proteins found on the plasma membrane of cells. They are involved in most physiological and pathophysiological functions and constitute the target of the majority of marketed drugs. Although these receptors have been historically elus...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215811/ https://www.ncbi.nlm.nih.gov/pubmed/25505664 http://dx.doi.org/10.1186/2193-9616-1-20 |