Cargando…

Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A(2B) adenosine receptor

PURPOSE: A(2B) receptor agonists are studied as possible therapeutic tools for a variety of pathological conditions. Unfortunately, medicinal chemistry efforts have led to the development of a limited number of potent agonists of this receptor, in most cases with a low or no selectivity versus the o...

Descripción completa

Detalles Bibliográficos
Autores principales: Dal Ben, Diego, Buccioni, Michela, Lambertucci, Catia, Thomas, Ajiroghene, Volpini, Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215817/
https://www.ncbi.nlm.nih.gov/pubmed/25505666
http://dx.doi.org/10.1186/2193-9616-1-24