Complex Impacts of PI3K/AKT Inhibitors to Androgen Receptor Gene Expression in Prostate Cancer Cells

BACKGROUND: Androgen deprivation therapy (ADT) is the first-line treatment to metastatic prostate cancer (PCa). However, sustained expression and function of the androgen receptor (AR) gene contribute to the progression of castration resistant prostate cancers (CRPC). Additionally, tumors can adapt...

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Detalles Bibliográficos
Autores principales: Liu, Liangliang, Dong, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215833/
https://www.ncbi.nlm.nih.gov/pubmed/25360799
http://dx.doi.org/10.1371/journal.pone.0108780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215833/
https://www.ncbi.nlm.nih.gov/pubmed/25360799
http://dx.doi.org/10.1371/journal.pone.0108780

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