Cargando…

Application of Screening Experimental Designs to Assess Chromatographic Isotope Effect upon Isotope-Coded Derivatization for Quantitative Liquid Chromatography–Mass Spectrometry

[Image: see text] Isotope effect may cause partial chromatographic separation of labeled (heavy) and unlabeled (light) isotopologue pairs. Together with a simultaneous matrix effect, this could lead to unacceptable accuracy in quantitative liquid chromatography–mass spectrometry assays, especially w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szarka, Szabolcs, Prokai-Tatrai, Katalin, Prokai, Laszlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215859/ https://www.ncbi.nlm.nih.gov/pubmed/24922593 http://dx.doi.org/10.1021/ac501309s

Ejemplares similares

Design and Exploratory Neuropharmacological Evaluation of Novel Thyrotropin-Releasing Hormone Analogs and Their Brain-Targeting Bioprecursor Prodrugs
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2013)

Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2009)

A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019)

Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications
por: Prokai, Laszlo, et al.
Publicado: (2021)

Quantitative Structure-Activity Relationships Predicting the Antioxidant Potency of 17β-Estradiol-Related Polycyclic Phenols to Inhibit Lipid Peroxidation
por: Prokai, Laszlo, et al.
Publicado: (2013)

17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics
por: Prokai, Laszlo, et al.
Publicado: (2020)

[β-Glu(2)]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2021)

Proteomics-Based Identification of Retinal Protein Networks Impacted by Elevated Intraocular Pressure in the Hypertonic Saline Injection Model of Experimental Glaucoma
por: Zaman, Khadiza, et al.
Publicado: (2023)

The Antagonist pGlu-βGlu-Pro-NH(2) Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor
por: De La Cruz, Daniel L., et al.
Publicado: (2021)

Phenolic Compounds Protect Cultured Hippocampal Neurons against Ethanol-Withdrawal Induced Oxidative Stress
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2009)

Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2021)

Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery
por: Merchenthaler, Istvan, et al.
Publicado: (2016)

Brain-Selective Estrogen Therapy Prevents Androgen Deprivation-Associated Hot Flushes in a Rat Model
por: Merchenthaler, Istvan, et al.
Publicado: (2020)

Derivatization of Levoglucosan for Compound-Specific δ(13)C Analysis by Gas Chromatography/Combustion/Isotope Ratio Mass Spectrometry
por: Zhang, Dongling, et al.
Publicado: (2020)

The Utility of Oligopeptidase in Brain-Targeting Delivery of an Enkephalin Analogue by Prodrug Design
por: Prokai-Tatrai, K, et al.
Publicado: (2008)

Direct Analysis in Real Time (DART) of an Organothiophosphate at Ultrahigh Resolution by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Tandem Mass Spectrometry
por: Prokai, Laszlo, et al.
Publicado: (2016)

Brain Delivery of Thyrotropin-Releasing Hormone via a Novel Prodrug Approach
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019)

Stable Carbon Isotope Analysis of Hexachlorocyclohexanes by Liquid–Liquid Extraction Gas Chromatography Isotope Ratio Mass Spectrometry: Method Evaluation and Applications
por: Gao, Cuiping, et al.
Publicado: (2022)

Quantitative Bioreactor Monitoring of Intracellular Bacterial Metabolites in Clostridiumautoethanogenum Using Liquid Chromatography–Isotope Dilution Mass Spectrometry
por: Safo, Laudina, et al.
Publicado: (2021)

Retina-Targeted Delivery of 17β-Estradiol by the Topically Applied DHED Prodrug
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2020)

Stable Isotope Analysis of Residual Pesticides via High Performance Liquid Chromatography and Elemental Analyzer–Isotope Ratio Mass Spectrometry
por: Yun, Hee Young, et al.
Publicado: (2022)

Quantitative determination of human serum testosterone via isotope dilution ultra-performance liquid chromatography tandem mass spectrometry
por: Sun, Guang, et al.
Publicado: (2020)

Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry
por: Wigger, Dominik, et al.
Publicado: (2019)

Determination of Alternaria Toxins in Sunflower Oil by Liquid Chromatography Isotope Dilution Tandem Mass Spectrometry
por: Tölgyesi, Ádám, et al.
Publicado: (2020)

Quantitative amino acid analysis by liquid chromatography‐tandem mass spectrometry using low cost derivatization and an automated liquid handler
por: Phipps, William S., et al.
Publicado: (2019)

Mitigating analyte to stable isotope labelled internal standard cross-signal contribution in quantitative liquid chromatography-tandem mass spectrometry
por: Radovanovic, Mirjana, et al.
Publicado: (2022)

Evaluation of honey authenticity in Lebanon by analysis of carbon stable isotope ratio using elemental analyzer and liquid chromatography coupled to isotope ratio mass spectrometry
por: El Hawari, Khaled, et al.
Publicado: (2021)

Stable Isotope Dilution Multidimensional Liquid Chromatography-Tandem Mass Spectrometry for Pancreatic Cancer Serum Biomarker Discovery
por: Yu, Kenneth H., et al.
Publicado: (2009)

Comparison of Six Automated Immunoassays With Isotope-Diluted Liquid Chromatography-Tandem Mass Spectrometry for Total Thyroxine Measurement
por: Yu, Songlin, et al.
Publicado: (2019)

Liquid Chromatography Tandem Mass/Mass Spectrometry for the Quantification of Fudosteine in Human Serum without Precolumn Derivatization
por: Fan, Peng-Cheng, et al.
Publicado: (2014)

Qualitative and Quantitative Analysis of Regional Cerebral Free Fatty Acids in Rats Using the Stable Isotope Labeling Liquid Chromatography–Mass Spectrometry Method
por: Hu, Ting, et al.
Publicado: (2020)

Determination of cyclamate in urine by derivatized gas chromatography-mass spectrometry
por: Idris, Mohd, et al.
Publicado: (2013)

Quantitating subcellular metabolism with multi-isotope imaging mass spectrometry
por: Steinhauser, Matthew L., et al.
Publicado: (2012)

Derivatization enhances analysis of estrogens and their bioactive metabolites in human plasma by liquid chromatography tandem mass spectrometry
por: Denver, Nina, et al.
Publicado: (2019)

Quantitative analysis of penicillins in porcine tissues, milk and animal feed using derivatisation with piperidine and stable isotope dilution liquid chromatography tandem mass spectrometry
por: van Holthoon, Frédérique, et al.
Publicado: (2010)

Comprehensive Lipidomic Workflow for Multicohort Population Phenotyping Using Stable Isotope Dilution Targeted Liquid Chromatography-Mass Spectrometry
por: Ryan, Monique J., et al.
Publicado: (2023)

Chromatographic Zinc Isotope Separation by Chelating Exchange Resin
por: Ding, Xingcheng, et al.
Publicado: (2010)

Utilizing liquid chromatography, ion mobility spectrometry, and mass spectrometry to assess INLIGHT™ derivatized N-linked glycans in biological samples
por: Butler, Karen E., et al.
Publicado: (2021)

Determination of perchlorate in infant formula by isotope dilution ion chromatography/tandem mass spectrometry
por: Wang, Z., et al.
Publicado: (2011)

Quantification of horse plasma proteins altered by xylazine using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry
por: MORI, Miwako, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ll32t3phb4o9aelb5amhhuins5