Versatile O-GlcNAc Transferase Assay for High-Throughput Identification of Enzyme Variants, Substrates, and Inhibitors

[Image: see text] The dynamic glycosylation of serine/threonine residues on nucleocytoplasmic proteins with a single N-acetylglucosamine (O-GlcNAcylation) is critical for many important cellular processes. Cellular O-GlcNAc levels are highly regulated by two enzymes: O-GlcNAc transferase (OGT) is re...

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Detalles Bibliográficos
Autores principales: Kim, Eun J., Abramowitz, Lara K., Bond, Michelle R., Love, Dona C., Kang, Dong W., Leucke, Hans F., Kang, Dae W., Ahn, Jong-Seog, Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215860/
https://www.ncbi.nlm.nih.gov/pubmed/24866374
http://dx.doi.org/10.1021/bc5001774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215860/
https://www.ncbi.nlm.nih.gov/pubmed/24866374
http://dx.doi.org/10.1021/bc5001774

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