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Downregulated Ku70 and ATM associated to poor prognosis in colorectal cancer among Chinese patients

BACKGROUND: Double-strand DNA breaks (DSBs) are a key factor in carcinogenesis. The necessary repair of DSBs is pivotal in maintaining normal cell division. To address the relationship between altered expression of DSB repair of proteins Ku70 and ataxia-telangiectasia mutated (ATM) in colorectal can...

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Detalles Bibliográficos
Autores principales: Lu, Yuanfang, Gao, Jingyan, Lu, Yuanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216044/
https://www.ncbi.nlm.nih.gov/pubmed/25368522
http://dx.doi.org/10.2147/OTT.S67814