Cargando…

ASPP2 Links the Apical Lateral Polarity Complex to the Regulation of YAP Activity in Epithelial Cells

The Hippo pathway, by tightly controlling the phosphorylation state and activity of the transcription cofactors YAP and TAZ is essential during development and tissue homeostasis whereas its deregulation may lead to cancer. Recent studies have linked the apicobasal polarity machinery in epithelial c...

Descripción completa

Detalles Bibliográficos
Autores principales: Royer, Christophe, Koch, Sofia, Qin, Xiao, Zak, Jaroslav, Buti, Ludovico, Dudziec, Ewa, Zhong, Shan, Ratnayaka, Indrika, Srinivas, Shankar, Lu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216074/
https://www.ncbi.nlm.nih.gov/pubmed/25360797
http://dx.doi.org/10.1371/journal.pone.0111384