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Enterovirus-71 Virus-Like Particles Induce the Activation and Maturation of Human Monocyte-Derived Dendritic Cells through TLR4 Signaling

Enterovirus 71 (EV71) causes seasonal epidemics of hand-foot-and-mouth disease and has a high mortality rate among young children. We recently demonstrated potent induction of the humoral and cell-mediated immune response in monkeys immunized with EV71 virus-like particles (VLPs), with a morphology...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Li, Hu, Yu-Chen, Liang, Cheng-Chao, Lin, Shih-Yeh, Liang, Yu-Chih, Yuan, Hui-Ping, Chiang, Bor-Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216083/
https://www.ncbi.nlm.nih.gov/pubmed/25360749
http://dx.doi.org/10.1371/journal.pone.0111496