LRRK2 Transport Is Regulated by Its Novel Interacting Partner Rab32

Leucine-rich repeat kinase 2 (LRRK2) is a multi-domain 280 kDa protein that is linked to Parkinson's disease (PD). Mutations especially in the GTPase and kinase domains of LRRK2 are the most common causes of heritable PD and are also found in sporadic forms of PD. Although the cellular function...

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Detalles Bibliográficos
Autores principales: Waschbüsch, Dieter, Michels, Helen, Strassheim, Swantje, Ossendorf, Edith, Kessler, Daniel, Gloeckner, Christian Johannes, Barnekow, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216093/
https://www.ncbi.nlm.nih.gov/pubmed/25360523
http://dx.doi.org/10.1371/journal.pone.0111632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216093/
https://www.ncbi.nlm.nih.gov/pubmed/25360523
http://dx.doi.org/10.1371/journal.pone.0111632

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