Combining Use of Captopril and Losartan Attenuates the Progress of Streptococcus pneumoniae-Induced Tympanosclerosis through the Suppression of TGF-β1 Expression

OBJECTIVES: In this study, using an Streptococcus pneumoniae-induced tympanosclerosis (TS) model, we explored the effects of captopril and losartan in the treatment of TS and the possible mechanisms. STUDY DESIGN: A prospective experimental animal study. METHODS: We set up the TS models in both guin...

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Detalles Bibliográficos
Autores principales: Yan, Wenqing, Li, Jianfeng, Chai, Renjie, Guo, Wentao, Xu, Lei, Han, Yuechen, Bai, Xiaohui, Wang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216096/
https://www.ncbi.nlm.nih.gov/pubmed/25360706
http://dx.doi.org/10.1371/journal.pone.0111620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216096/
https://www.ncbi.nlm.nih.gov/pubmed/25360706
http://dx.doi.org/10.1371/journal.pone.0111620

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