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Combining Use of Captopril and Losartan Attenuates the Progress of Streptococcus pneumoniae-Induced Tympanosclerosis through the Suppression of TGF-β1 Expression

OBJECTIVES: In this study, using an Streptococcus pneumoniae-induced tympanosclerosis (TS) model, we explored the effects of captopril and losartan in the treatment of TS and the possible mechanisms. STUDY DESIGN: A prospective experimental animal study. METHODS: We set up the TS models in both guin...

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Detalles Bibliográficos
Autores principales:	Yan, Wenqing, Li, Jianfeng, Chai, Renjie, Guo, Wentao, Xu, Lei, Han, Yuechen, Bai, Xiaohui, Wang, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216096/ https://www.ncbi.nlm.nih.gov/pubmed/25360706 http://dx.doi.org/10.1371/journal.pone.0111620

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