Cargando…

ELMO1 Is Upregulated in AML CD34+ Stem/Progenitor Cells, Mediates Chemotaxis and Predicts Poor Prognosis in Normal Karyotype AML

Both normal as well leukemic hematopoietic stem cells critically depend on their microenvironment in the bone marrow for processes such as self-renewal, survival and differentiation, although the exact pathways that are involved remain poorly understood. We performed transcriptome analysis on primit...

Descripción completa

Detalles Bibliográficos
Autores principales: Capala, Marta E., Vellenga, Edo, Schuringa, Jan Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216115/
https://www.ncbi.nlm.nih.gov/pubmed/25360637
http://dx.doi.org/10.1371/journal.pone.0111568