Cargando…

From Genes to Protein Mechanics on a Chip

Single-molecule force spectroscopy enables mechanical testing of individual proteins, however low experimental throughput limits the ability to screen constructs in parallel. We describe a microfluidic platform for on-chip protein expression and measurement of single-molecule mechanical properties....

Descripción completa

Detalles Bibliográficos
Autores principales: Otten, Marcus, Ott, Wolfgang, Jobst, Markus A., Milles, Lukas F., Verdorfer, Tobias, Pippig, Diana A., Nash, Michael A., Gaub, Hermann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216144/
https://www.ncbi.nlm.nih.gov/pubmed/25194847
http://dx.doi.org/10.1038/nmeth.3099