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From Genes to Protein Mechanics on a Chip
Single-molecule force spectroscopy enables mechanical testing of individual proteins, however low experimental throughput limits the ability to screen constructs in parallel. We describe a microfluidic platform for on-chip protein expression and measurement of single-molecule mechanical properties....
Autores principales: | Otten, Marcus, Ott, Wolfgang, Jobst, Markus A., Milles, Lukas F., Verdorfer, Tobias, Pippig, Diana A., Nash, Michael A., Gaub, Hermann E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216144/ https://www.ncbi.nlm.nih.gov/pubmed/25194847 http://dx.doi.org/10.1038/nmeth.3099 |
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