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Ligand Binding and Activation of PPARγ by Firemaster(®) 550: Effects on Adipogenesis and Osteogenesis in Vitro

Background: The use of alternative flame retardants has increased since the phase out of pentabromodiphenyl ethers (pentaBDEs). One alternative, Firemaster® 550 (FM550), induces obesity in rats. Triphenyl phosphate (TPP), a component of FM550, has a structure similar to that of organotins, which are...

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Detalles Bibliográficos
Autores principales: Pillai, Hari K., Fang, Mingliang, Beglov, Dmitri, Kozakov, Dima, Vajda, Sandor, Stapleton, Heather M., Webster, Thomas F., Schlezinger, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216168/
https://www.ncbi.nlm.nih.gov/pubmed/25062436
http://dx.doi.org/10.1289/ehp.1408111