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Effects of Tet-Induced Oxidation Products of 5-Methylcytosine on DNA Replication in Mammalian Cells

[Image: see text] Recently 5-hydroxymethyl-2′-deoxycytidine (5hmdC), 5-formyl-2′-deoxycytidine (5fdC), and 5-carboxyl-2′-deoxycytidine (5cadC) were discovered in mammalian DNA as oxidation products of 5-methyl-2′-deoxycytidine (5mdC) induced by the ten-eleven translocation family of enzymes. These o...

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Detalles Bibliográficos
Autores principales: Ji, Debin, You, Changjun, Wang, Pengcheng, Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216192/
https://www.ncbi.nlm.nih.gov/pubmed/24979327
http://dx.doi.org/10.1021/tx500169u