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Total Synthesis of the Aristolochic Acids, Their Major Metabolites, and Related Compounds

[Image: see text] Plants from the Aristolochia genus have been recommended for the treatment of a variety of human ailments since the time of Hippocrates. However, many species produce the highly toxic aristolochic acids (AAs), which are both nephrotoxic and carcinogenic. For the purposes of extensi...

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Detalles Bibliográficos
Autores principales: Attaluri, Sivaprasad, Iden, Charles R., Bonala, Radha R., Johnson, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216193/
https://www.ncbi.nlm.nih.gov/pubmed/24877584
http://dx.doi.org/10.1021/tx500122x