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Heterogeneous Preferential Solvation of Water and Trifluoroethanol in Homologous Lysozymes

[Image: see text] Cytoplasmic osmolytes can significantly alter the thermodynamic and kinetic properties of proteins relative to those under dilute solution conditions. Spectroscopic experiments of lysozymes in cosolvents indicate that such changes may arise from the heterogeneous, site-specific hyd...

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Detalles Bibliográficos
Autores principales: Arthur, Evan J., King, John T., Kubarych, Kevin J., Brooks, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216199/
https://www.ncbi.nlm.nih.gov/pubmed/24823618
http://dx.doi.org/10.1021/jp501132z