Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound

[Image: see text] Compounds active at neurotensin receptors (NTS1 and NTS2) exert analgesic effects on different types of nociceptive modalities, including thermal, mechanical, and chemical stimuli. The NTS2 preferring peptide JMV-431 (2) and the NTS2 selective nonpeptide compound levocabastine (6)...

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Detalles Bibliográficos
Autores principales: Thomas, James B., Giddings, Angela M., Wiethe, Robert W., Olepu, Srinivas, Warner, Keith R., Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P., Gilmour, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216214/
https://www.ncbi.nlm.nih.gov/pubmed/24856674
http://dx.doi.org/10.1021/jm5003843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216214/
https://www.ncbi.nlm.nih.gov/pubmed/24856674
http://dx.doi.org/10.1021/jm5003843

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