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Primoridal germ cell specification: a context-dependent cellular differentiation event

During embryonic development, the foundation of the germline is laid by the specification of primordial germ cells (PGCs) from the postimplantation epiblast via bone morphogenetic protein (BMP) and WNT signalling. While the majority of epiblast cells undergo differentiation towards somatic cell line...

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Detalles Bibliográficos
Autores principales: Günesdogan, Ufuk, Magnúsdóttir, Erna, Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216466/
https://www.ncbi.nlm.nih.gov/pubmed/25349452
http://dx.doi.org/10.1098/rstb.2013.0543