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Primoridal germ cell specification: a context-dependent cellular differentiation event
During embryonic development, the foundation of the germline is laid by the specification of primordial germ cells (PGCs) from the postimplantation epiblast via bone morphogenetic protein (BMP) and WNT signalling. While the majority of epiblast cells undergo differentiation towards somatic cell line...
Autores principales: | Günesdogan, Ufuk, Magnúsdóttir, Erna, Surani, M. Azim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216466/ https://www.ncbi.nlm.nih.gov/pubmed/25349452 http://dx.doi.org/10.1098/rstb.2013.0543 |
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