Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

We have previously demonstrated that Stat3 regulates lysosomal mediated-programmed cell death (LM-PCD) during mouse mammary gland involution in vivo. However, the mechanism that controls the release of lysosomal cathepsins to initiate cell death in this context has not been elucidated. We show here...

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Detalles Bibliográficos
Autores principales: Sargeant, Timothy J., Lloyd-Lewis, Bethan, Resemann, Henrike K., Ramos-Montoya, Antonio, Skepper, Jeremy, Watson, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216597/
https://www.ncbi.nlm.nih.gov/pubmed/25283994
http://dx.doi.org/10.1038/ncb3043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216597/
https://www.ncbi.nlm.nih.gov/pubmed/25283994
http://dx.doi.org/10.1038/ncb3043

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