Downregulation of MDR1 Gene by Cepharanthine Hydrochloride Is Related to the Activation of c-Jun/JNK in K562/ADR Cells

The purpose of the study was to determine the signal transduction mechanism of cepharanthine hydrochloride (CH) on reversing tumor multidrug resistance. RT-PCR and Western blot analysis were used to determine the effects of CH on the expression of MDR1 mRNA and P-glycoprotein in K562/ADR cells when...

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Detalles Bibliográficos
Autores principales: Han, Li, Wang, Yafeng, Guo, Xiaojuan, Zhou, Yubing, Zhang, Jingmin, Wang, Ning, Jiang, Jinhua, Ma, Fang, Wang, Qingduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216687/
https://www.ncbi.nlm.nih.gov/pubmed/25386557
http://dx.doi.org/10.1155/2014/164391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216687/
https://www.ncbi.nlm.nih.gov/pubmed/25386557
http://dx.doi.org/10.1155/2014/164391

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