Astragalus Polysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways

Background. Doxorubicin, a potent chemotherapeutic agent, is associated with acute and chronic cardiotoxicity, which is cumulatively dose-dependent. Astragalus polysaccharide (APS), the extract of Astragalus membranaceus with strong antitumor and antiglomerulonephritis activity, can effectively alle...

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Detalles Bibliográficos
Autores principales: Cao, Yuan, Ruan, Yang, Shen, Tao, Huang, Xiuqing, Li, Meng, Yu, Weiwei, Zhu, Yuping, Man, Yong, Wang, Shu, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216718/
https://www.ncbi.nlm.nih.gov/pubmed/25386226
http://dx.doi.org/10.1155/2014/674219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216718/
https://www.ncbi.nlm.nih.gov/pubmed/25386226
http://dx.doi.org/10.1155/2014/674219

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