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LSD1 controls metastasis of androgen-independent prostate cancer cells through PXN and LPAR6

Lysine-specific demethylase 1 (LSD1) was shown to control gene expression and cell proliferation of androgen-dependent prostate cancer (PCa) cells, whereas the role of LSD1 in androgen-independent metastatic prostate cancer remains elusive. Here, we show that depletion of LSD1 leads to increased mig...

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Detalles Bibliográficos
Autores principales: Ketscher, A, Jilg, C A, Willmann, D, Hummel, B, Imhof, A, Rüsseler, V, Hölz, S, Metzger, E, Müller, J M, Schüle, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216900/
https://www.ncbi.nlm.nih.gov/pubmed/25285406
http://dx.doi.org/10.1038/oncsis.2014.34